Experiment 381653
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Echinacea purpurea (ASTERACEAE) |
| Citation | MULLINS,RJ:. (1998). ECHINACEA-ASSOCIATED ANAPHYLAXIS.. 1998(168) |
| Amount utilized | |
| Compound isolated | |
| Disease | A WOMAN WITH ATOPY EXPERIENCED ANALPHYLAXIS AFTER TAKING, AMONG OTHER DIETARY SUPPLEMENTS, A COMMERICAL EXTRACT OF ECHINACEA. HYPERSENSITIVITY WAS CONFIRMED BY SKINPRICK AND RAST TESTING. REGULAR INGESTION OF ECHINACEAE BY UP TO 5% OF SURVEYED PATIENTS WITH ATOPY, COMBINED WITH DETECTION OF ECHINACEA-BINDING IGE IN ATOPIC SUBJECTS (19% BY SKIN TESTING; 20% WITH MODERATE TO STRONG REACTIVITY BY RAST TESTING), RAISES THE POSSIBILITY OF SEVERE ALLERGIC REACTIONS, EVEN WITH FIRST-TIME USE, DUE TO CROSS-REACTIVITY WITH OTHER STRUCTURALLY SIMILAR ALLERGENS. |
| Dose amount | 3.825 GM |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Per unit | PERSON |
| Dose expression | DOSE |
| Extract | HYDRO-ALCOHOLIC EXT |
| Gender | FEMALE |