Experiment 389892

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

LOBELINE

Details

PropertyValue
Pharmacology
DOPAMINE UPTAKE INHIBITION
OrganismEmpty organism
CitationTENG,LH: CROOKS,PA: DWOSKIN,LP:. (1998). LOBELINE DISPLACES [3H]DIHYDROTETRABENAZINE BINDING AND RELEASES [3H]DOPAMINE FROM RAT STRIATAL SYNAPTIC VESICLES: COMPARISON WITH D-AMPHETAMINE.. 71(1)
Amount utilized
Compound isolated
DiseaseRESULTS SUGGEST THAT COMPOUND INHIBITS DA UPTAKE BY INTERACTING WITH THE DIHYDROTETRABENZING BINDING SITE ON THE VESICULAR MONOAMINE TRANSPORTER.
Dose amount0.90 MICROMOLS
Number2
Qualitative resultACTIVE
AnimalRAT
Dose expressionIC50