Experiment 398093
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Panax ginseng (ARALIACEAE) |
| Citation | LE GAL,M: CATHEBRAS,P: STRUBY,K:. (1996). PHARMATON CAPSULES IN THE TREATMENT OF FUNCTIONAL FATIGUE: A DOUBLE-BLIND STUDY VERSUS PLACEBO EVALUATED BY A NEW METHODOLOGY.. 10(1) |
| Amount utilized | |
| Compound isolated | |
| Disease | A NEW METHOD FOR THE EVALUATION OF THE COMPLAINTS REPORTED BY PATIENTS SUFFERING FROM FUNCTIONAL FATIGUE WAS INVESTED IN THE COURSE OF A MULTICENTRE, COMPARATIVE, DOUBLE-BLIND, CLINICAL STUDY OF GINSENG VERSUS PLACEBO IN A TOTAL OF 232 PATIENTS AGED BETWEEN 25 AND 60 YEARS. THE PRINCIPLE OF THE STUDY WAS TO ALLOW THE PATIENT TO CHOOSE, FROM A PRE-ESTABLISHED LIST OF 20 SUGGESTIONS, THE FIVE ITEMS THAT BEST DESCRIBED HIS COMPLAINTS. AN INDIVIDUAL FATIGUE SCORE WAS CALCULATED FOR EACH PATIENT ON THE BASIS OF THE SUM OF THE SCORES GIVEN BY THE PATIENT FOR EACH OF THE FIVE ITEMS SELECTED (EACH ITEM WAS EVALUATED ACCORDING TO A 4-POINT TIME SCALE). THIS SCORE WAS CALCULATED ON DAY 0 AFTER 21 AND 42 DAYS TREATMENT. THE ANALYSIS OF THE FATIGUE SCORES AT THE END OF THE STUDY SHOWED A STATISTICALLY SIGNIFICANT DIFFERENCE IN FAVOUR OF THE GINSENG GROUP. THE GLOBAL ASSESSMENT OF THE EFFICACY OF THE TREATMENT (GIVEN BY THE LAVESTIGATORS AND BY THE PATIENTS) DEMONSTRATED THE SUPERIOR EFFECT OF THE GINSENG, WAEREAS THE GLOBAL ASSESSMENT OF THE TOLERABILITY SHOWED NO DIFFERENCE BETWEEN THE TOW TREATMENTS. |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Dose expression | DOSE |
| Extract | HYDRO-ALCOHOLIC EXT |
| Gender | GIVEN TO BOTH SEXES |