Experiment 417048

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

BAFILOMYCIN A-1

Details

PropertyValue
Pharmacology
LYSOSOMAL PROTEIN DEGRADATION INHIBITION
OrganismEmpty organism
CitationYOSHIMORI,T: YAMAMOTO,A: MORIYAMA,Y: FUTAI,M: TASHIRO,Y:. (1991). BAFILOMYCIN A1, A SPECIFIC INHIBITOR OF VACULAR-TYPE H+ -ATPASE, INHIIBITS ACIDIFACTION AND PROTEIN DEGRADATION IN LYSOSOMES OF CULTURED CELLS.. 266(26)
Amount utilized
Compound isolated
DiseaseEPIDERMAL GROWTH FACTOR WAS INTERNALIZED INTO CELLS, BUT ITS DEGRADATION WAS INHIBITED ALMOST 100%.
Dose amount1.0 MICROMOLS
Number1
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionCONC USED