Experiment 419098

Worktypes

PATENT DESCRIBEDPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

ASIATICOSIDE

Alerts

BIOLOGICAL ACTIVITY REPORTED HAS BEEN PATENTED.VS.5-HT-INDUCED CONTRACTIONS.DATA INCOMPLETE - DERIVED FROM AN ABSTRACT.

Details

PropertyValue
Pharmacology
SEROTONIN (5-HT) RECEPTOR BLOCKING EFFECT
OrganismCentella asiatica (APIACEAE)
CitationDE SOUZA,NJ: SHAH,V: DESAI,PD: INAMDAR,PK: D'SA,A: AMMANAMANCHI,R: DOHADWALLA,AN: LAKDAWALA,AD: MANDREKAR,SS: BLUMBACH J:. (1990). PREPARATION OF 2,3,23-TRIHYDROXYURO-12-ENE AND ITS DERIVATIVES AS SEROTONERGIC RECEPTOR ANTAGONISTS.. ()
Amount utilized
Compound isolated
DiseaseCONTRACTIONS OF ILEUM WERE INHIBITED 34.5%.
Dose amount100.0 MCG
Number3
Qualitative resultACTIVE
AnimalGUINEA PIG
Per unitML
Dose expressionCONC USED