Experiment 420307
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Empty organism |
| Citation | NAKAYAMA,KI: LOH,DY:. (1992). NO REQUIREMENT FOR P56LCK IN THE ANTIGEN-STIMULATED CLONAL DELETION OF THYMOCYTES.. 257(5066) |
| Amount utilized | |
| Compound isolated | |
| Disease | P56-LCK IS A PROTEIN-TYROSINE KINASE ASSOCIATED WITH T-CELL RECEPTOR. CMPD INHIBITED T-CELL ACTIVATION OF CD4+CD8- TRANSGENIC CELLS, BUT DID NOT INHIBIT ANTIGEN-INDUCED CLONAL DELETION OF CD4+CD8+TCRLO TRANSGENIC CELLS, SUGGESTING THAT SEPARATE POST-RECEPTOR PATHWAYS WERE INVOLVED. |
| Dose amount | 400.0 NANOMOLS |
| Number | 2 |
| Qualitative result | ACTIVE |
| Dose expression | CONC USED |