Experiment 420581

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

WORTMANNIN

Details

PropertyValue
Pharmacology
CATECHOLAMINE INHIBITORY EFFECT
OrganismEmpty organism
CitationOHARA-IMAZUMI,M: SAKURAI,T: NAKAMURA,S: NAKANISHI,S: MATSUDA,Y: MURAMATSU,S: NONOMURA,Y: KUMAKURA,K:. (1992). INHIBITION OF CA2-DEPENDENT CATECHOLAMINE RELEASE BY MYOSIN LIGHT CHAIN KINASE INHIBITOR, WORTANNIN, IN ADRENAL CHROMAFFIN CELLS.. 185(3)
Amount utilized
Compound isolated
DiseaseCMPD INHIBITED CA2+-EVOKED CATECHOL RELEASE IN DIGITONIN-PERMEABILIZED CELLS.
Dose amount1.0 MICROMOLS
Number2
Qualitative resultACTIVE
Dose expressionIC50