Experiment 425619

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

GINKGOLIDE B

Details

PropertyValue
Pharmacology
PLATELET ACTIVATING FACTOR BINDING INHIBITION
OrganismEmpty organism
CitationDOMINGO,MT: PIRO,F: BROQUET,E: AUCLAIR,E: CHABRIER,PE: BRAQUET,P:. (1992). REVERSIBLE OF IRREVERSIBLE MODIFICATION OF [3H]PAF BINDING ON RABIT PLATELET MEMBRANES DIFFERENTIATES VARIOUS PAF RECEPTOR ANTAGONISTS.. 27(8)
Amount utilized
Compound isolated
DiseaseCOMPOUND DID NOT ALTER DISSOCIATION CONSTANT OF PAF, BUT DID REDUCE THE MAXIMUM NUMBER OF BINDING SITES.
Dose amount200.0 NANOMOLS
Number1
Qualitative resultACTIVE
AnimalRABBIT
Dose expressionIC50