Experiment 427147

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

STREPTOMYCES ANTIBIOTIC WS-9326-A

Details

PropertyValue
Pharmacology
SPASMOLYTIC ACTIVITY
Administration routeINTRATRACHEAL
OrganismStrptomyces violaceusniger (STREPTOMYCETACEAE)
CitationHASHIMOTO,M: HAYASHI,K: MURAI,M: FUJII,T: NISHIKAWA,M: KIYOTO,S: OKUHARA,M: KOHSAKA,M: IMANAKA,H:. (1992). WS9326A, A NOVEL TACHYKININ ANTAGONIST ISOLATED FROM STREPTOMYCES VIOLACEUSNIGER NO. 9326 II. BIOLOGICAL AND PHARMACOLOGICAL PROPERTIES OF WS9326A AND TETRAHYDRO-WS9329A (FK224).. 45(7)
Amount utilized
Compound isolated
DiseaseCMPD INHIBITED NEUROKININ A-INDUCED INCREASE IN AIRWAY RESISTANCE.
Dose amount0.29 MG
Number22
Qualitative resultACTIVE
AnimalGUINEA PIG
Per unitKG
Dose expressionIC50