Experiment 427776

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

STREPTOMYCES ANTIBIOTIC WS-009-A

Details

PropertyValue
Pharmacology
RECEPTOR BINDING(ENDOTHELIAL) DECREASED
OrganismEmpty organism
CitationMIYATA,S: HASHIMOTO,M: FUJIE,K: SHOUHO,M: SOGABE,K: KIYOTO,S: OKUHARA,M: KOHSAKA,M:. (1992). WS009 A AND B, NEW ENDOTHELIN RECEPTOR ANTAGONISTS ISOLATED FROM STREPTOMYCES SP.NO.89009. II. BIOLOGICAL CHARACTERIZATION OF WS009 A AND B.. 45(7)
Amount utilized
Compound isolated
DiseaseHUMAN AORTA TISSUE WAS USED. ENDOTHILIN-1 RECEPTOR BINDING WAS ASSAYED.
Dose amount13.0 MICROMOLS
Number9
Qualitative resultACTIVE
Dose expressionIC50