Experiment 428338
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Phoma species (COELOMYCETES) |
| Citation | DAWSON,MJ: FARTHING,JE: MARSHALL,PS: MIDDLETON,RF: O'NEILL,MJ: SHUTTLEWORTH,A: STYLLI,C: TAIT,RM: TAYLOR,PM: WILDMAN,HG: BUSS,AD: LANGLEY,D: HAYES,MV:. (1992). THE SQUALESTATINS, NOVEL INHIBITORS OF SQUALENE SYNTHASE PRODUCED BY A SPECIES OF PHOMA. I. TAXONOMY, FERMENTATION, ISOLATION, PHYSICO-CHEMICAL PROPERTIES AND BIOLOGICAL ACTIVITY.. 5(45) |
| Amount utilized | |
| Compound isolated | |
| Disease | MICROSOMAL SQUALENE SYNTHASE FROM CANDIDA ALBICANS WAS USED. |
| Dose amount | 5.0 NANOMOLS |
| Number | 14 |
| Qualitative result | ACTIVE |
| Dose expression | IC50 |