Experiment 440394

Worktypes

STRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

PSORALEN

Details

PropertyValue
Pharmacology
DNA BINDING EFFECT
OrganismEmpty organism
CitationGIA,O: MAGNO,SM: GARBESI,A: COLONNA,FP: PALUMBO,M:. (1992). SEQUENCE SPECIFICITY OF PSORALEN PHOTOBINDING TO DNA: A QUANITITIATIVE APPROACH.. 31(47)
Amount utilized
Compound isolated
DiseaseTHE EXTENT OF PHOTOREACTION OF -METHOXY ADDUCT OF COMPOUND WITH DNA IS A FUNCTION OF THE BASE SEQUENCE. THE REACTIVITY DECREASED 5'-(GTAC)-N TO 5'-TATA TO TERMINAL 5'-TA.
Dose amount19.0 MICROMOLS
Number2
Qualitative resultACTIVE
Dose expressionCONC USED