Experiment 441759

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOEFFECTS DUE TO A COMBINATION OF DRUGS

Compounds isolated

AFROMOSIN

Alerts

VS.12-O-TETRADECANOYLPHORBOL-13-ACETATE(TPA)-INDUCED CARCINOGENESIS.VS.DMBA-INDUCED CARCINOGENESIS.A MIXTURE OF PURE COMPOUNDS WAS USED TO OBTAIN THE REPORTED EFFECT.

Details

PropertyValue
Pharmacology
ANTITUMOR-PROMOTING ACTIVITY
Administration routeEXTERNAL
OrganismWisteria brachybotrys (FABACEAE)
CitationKONOSHIMA,T: KOKUMAI,M: KOZUKA,M: TOKUDA,H: NISHINO,H: IWASHIMA,A:. (1992). ANTI-TUMOR-PROMOTING ACTIVITIES OF AFROMOSIN AND SOYASAPONIN ISOLATED FROM WISTARIA BRACHYBOTRYS.. 55(12)
Amount utilized
Compound isolated
DiseaseA COMBINATION OF AFROMOSIN AND SOYASAPONIN I WAS USED.
Dose amount2.5 NANOMOLS
Number4
Qualitative resultACTIVE
AnimalMOUSE
Dose expressionMINIMUM TOXIC DOSE