Experiment 445731

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

SCOPADULCIC ACID B

Alerts

VS.12-O-TETRADECANOYLPHORBOL-13-ACETATE(TPA)-INDUCED CARCINOGENESIS.VS.DMBA-INDUCED CARCINOGENESIS.

Details

PropertyValue
Pharmacology
ANTITUMOR-PROMOTING ACTIVITY
Administration routeEXTERNAL
OrganismEmpty organism
CitationNISHINO,H: HAYASHI,T: ARISAWA,M: SATOMI,Y: IWASHIMA,A:. (1993). ANTITUMOR-PROMOTING ACTIVITY OF SCOPADULCIC ACID B, ISOLATED FROM THE MEDICINAL PLANT SCOPARIA DULCIS L.. 50(2)
Amount utilized
Compound isolated
DiseaseTHE FIRST TUMOR APPEARED AT WEEK II IN THE TREATED MICE AS COMPARED TO WEEK 6 IN CONTROL MICE. IN ADDITION, TREATED MICE HAD 1.9 TUMORS/MOUSE VS. 6.0 TUMOR/MOUSE IN CONTROL ANIMALS.
Dose amount162.0 NANOMOLS
Number2
Qualitative resultACTIVE
AnimalMOUSE
Dose expressionCONC USED