Experiment 446059

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOEFFECTS DUE TO A COMBINATION OF DRUGS

Compounds isolated

BRYOSTATIN 1

Alerts

A MIXTURE OF PURE COMPOUNDS WAS USED TO OBTAIN THE REPORTED EFFECT.DATA INCOMPLETE - DERIVED FROM AN ABSTRACT.

Details

PropertyValue
Pharmacology
LYMPHOCYTE(B) STIMULATION
Administration routeIV
OrganismEmpty organism
CitationTUTTLE,TM: BETHKE,KP: INGE,TH: MC CRADY,CW: PETTIT,GR: BEAR,HD:. (1992). BRYOSTAIN 1-ACTIVATED T CELLS CAN TRAFFIC AND MEDIATE TUMOR REGRESSION.. 52(6)
Amount utilized
Compound isolated
DiseaseLYMPHOCYTES STIMULATED BY A COMBINATION OF BRYOSTATIN-1 AND CALCIUM IONOPHORE INOMYCIN WERE INJECTED INTO SPLENECTOMIZED MICE BEARING EITHER MCA-105 OR MCA-203 TUMORS. MCA-105 TUMOR REGRESSION WAS NOTED BUT NOT MCA-203.
Number1
Qualitative resultACTIVE
AnimalMOUSE
Dose expressionDOSE