Experiment 446193

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

SQUALESTATIN 1

Details

PropertyValue
Pharmacology
CHOLESTEROL SYNTHESIS INHIBITION
OrganismEmpty organism
CitationBAXTER,A: FITZGERALD,BJ: HUTSON,JL: MC CARTHY,AD: MOTTERAM,JM: ROSS,BC: SAPRA,M: SNOWDEN,MA: WATSON,NS: WILLIAMS,RJ: WRIGHT,C:. (1992). SQUALESTATIN 1, A POTENT INHIBITOR OF SQUALENE SYNTASE, WHICH LOWERS SERUM CHOLESTEROL IN VIVO.. 267(17)
Amount utilized
Compound isolated
Dose amount39.0 NANOMOLS
Number2
Qualitative resultACTIVE
Dose expressionIC50