Experiment 446822

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

RHEIN ANTHRONE

Details

PropertyValue
Pharmacology
LAXATIVE EFFECT
OrganismEmpty organism
CitationNIJS,G: DE WITTE,P: GEBOES,K: MEULEMANS,A: SCHUURKES,J: LEMLI,J:. (1993). INFLUENCE OF RHEIN ANTHRONE ON PERISTALTIC REFLEX ON GUINEA-PIG ISOLATED ILEUM: INVOLVEMENT OF PROSTAGLANDINS.. 108(1)
Amount utilized
Compound isolated
DiseaseCMPD INCREASED LONGITUDINAL MUSCLE TENSION, INTRALUMINAL PRESSURE AND VOLUME DISPLACEMENT. EFFECT INHIBITED BY BW755C, INDOMETHACIN AND PG ANTAGONIST SC19220.
Dose amount3.0 MILLIMOLS
Number1
Qualitative resultACTIVE
AnimalGUINEA PIG
Dose expressionCONC USED