Experiment 446851

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODEPATENT DESCRIBED

Compounds isolated

TETRANDRINE,(+):

Alerts

BIOLOGICAL ACTIVITY REPORTED HAS BEEN PATENTED.DATA INCOMPLETE - DERIVED FROM AN ABSTRACT.

Details

PropertyValue
Pharmacology
ANTITUMOR ACTIVITY
Administration routeROUTE NOT GIVEN
OrganismEmpty organism
CitationVAN DYKE,K:. (1992). METHOD FOR POTENTIATING PRIMARY DRUGS IN TREATING MULTIDRUG RESISTANT CELLS.. ()
Amount utilized
Compound isolated
DiseaseCOMPOUND REVERSES DRUG-RESISTANCE APPARENTLY BY INHIBITING OR REVERSING GLYCOPROTEIN PUMP. DOSE GIVEN OVER 4 DAYS WAS FOLLOWED BY DOXORUBICIN. TUMOR INHIBITED BY 54% DESPITE NOMINAL DOXORUBICIN RESISTANCE.
Dose amount3.0 MG
Number3
Qualitative resultACTIVE
AnimalMOUSE
Dose expressionDOSE