Experiment 449045

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

TOPOTECAN*

Details

PropertyValue
Pharmacology
GENE EXPRESSION INHIBITION
OrganismEmpty organism
CitationLI,CJ: ZHANG,LJ: DEZUBE,BJ: CRUMPACKER,CS: PARDEE,AB:. (1993). THREE INHIBITORS OF TYPE 1 HUMAN IMMUNODEFICENCY VIRUS LONG TERMINAL REPEAT-DIRECTED GENE EXPRESSION AND VIRUS REPLICATION.. 90(5)
Amount utilized
Compound isolated
DiseaseVS.PHORBOL-12-MYRISTATE 13-ACETATE INDUCED CELL STIMULATION. HIV-1 LONG TERMINAL REPEAT DIRECTED GENE EXPRESSION WAS INHIBITED.
Dose amount0.05 MICROMOLS
Number1
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50