Experiment 449764
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | INTRAGASTRIC |
| Organism | Empty organism |
| Citation | K,YAMAUCHI: S,KUWANO:. (1992). METABOLIC ACTIVATION OF SENNOSIDE C IN MICE-SYNERGISTIC ACTION OF ANTHRONES.. 15(1) |
| Amount utilized | |
| Compound isolated | |
| Disease | COMPOUND IS METABOLIZED BY GUT BACTERIA TO ANTHRONES, ALOE-EMODIN AND RHEIN, WHICH ARE LAXATATIOUS. PRETREATMENT WITH CHLORAMPHENICOL INHIBITS EFFECT. |
| Dose amount | 11.6 MICROMOLS |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | RAT |
| Per unit | KG |
| Dose expression | DOSE |