Experiment 451347

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

DIALLYL SULFIDE

Details

PropertyValue
Pharmacology
CYTOCHROME P450 INDUCTION
Administration routeINTRAGASTRIC
OrganismEmpty organism
CitationPAN,JM: HONG,JY: MA,BL: NING,SM: PARANAWITHAN,SR: YANG,CS:. (1993). TRANSCRIPTIONAL ACTIVATION OF CYTOCHROME P450 2B1/2 GENES IN RAT LIVER BY DIALLYL SULFIDE, A COMPOUND DERIVED FROM GARLIC.. 302(2)
Amount utilized
Compound isolated
Disease12 HR AFTER SINGLE DOSE, MRNA LEVELS OF P450 2B1 AND 2B2 WERE INCREASED WHILE THOSE OF 2E1 WERE UNCHANGED. EFFECT BLOCKED BY ALPHA-AMANITIN.
Dose amount200.0 MG
Number2
Qualitative resultINACTIVE
AnimalRAT
Per unitKG
Dose expressionDOSE