Experiment 452757

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

NARINGENIN

Details

PropertyValue
Pharmacology
CYTOCHROME P450 INHIBITION
OrganismEmpty organism
CitationFUHR,U: KLITTICH,K: STAIB,AH:. (1993). INHIBITORY EFFECT OF GRAPEFRUIT JUICE AND ITS BITTER PRINCIPAL, NARINGENIN, ON CYP1A2 DEPENDENT METABOLISM OF CAFFEINE IN MAN.. 35(4)
Amount utilized
Compound isolated
DiseaseCOMPOUND INHIBITED CAFFEINE 3-DEMETHYLATION BY P450 CYP1A2.
Dose amount125.0 MICROMOLS
Number1
Qualitative resultACTIVE
AnimalHUMAN ADULT
Dose expressionCONC USED