Experiment 453348

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE

Compounds isolated

THIOCYANATE,ISO: BENZYL:

Alerts

MICROSOMAL INHIBITION OF OXIDATION OF 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE TO 4-HYDROXY COMPOUND.

Details

PropertyValue
Pharmacology
MICROSOMAL METABOLIZING SYSTEM INHIBITION
Administration routeINTRAGASTRIC
OrganismEmpty organism
CitationGUO,Z: SMITH,TJ: WANG,E: EKLIND,KI: CHUNG,FL: YANG,CS:. (1993). STRUCTURE-ACTIVITY RELATIONSHIPS OF ARYLALKYL ISOTHIOCYANATES FOR THE INHIBITION OF 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE METABOLISM AND THE MODULATION OF XENOBIOTIC-METABOLIZING ENYZMES IN RATS AND MICE.. 14(6)
Amount utilized
Compound isolated
Dose amount1.0 MILLIMOLS
Number20
Qualitative resultACTIVE
AnimalRAT
Per unitKG
Dose expressionDOSE