Experiment 453357

Worktypes

STRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

THIOCYANATE,ISO: 4-PHENYL-BUTYL:

Alerts

MICROSOMAL INHIBITION OF OXIDATION OF 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE TO 4-HYDROXY COMPOUND.

Details

PropertyValue
Pharmacology
MICROSOMAL METABOLIZING SYSTEM INHIBITION
OrganismEmpty organism
CitationGUO,Z: SMITH,TJ: WANG,E: EKLIND,KI: CHUNG,FL: YANG,CS:. (1993). STRUCTURE-ACTIVITY RELATIONSHIPS OF ARYLALKYL ISOTHIOCYANATES FOR THE INHIBITION OF 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE METABOLISM AND THE MODULATION OF XENOBIOTIC-METABOLIZING ENYZMES IN RATS AND MICE.. 14(6)
Amount utilized
Compound isolated
Dose amount70.0 NANOMOLS
Number5
Qualitative resultACTIVE
AnimalRAT
Dose expressionIC50