Experiment 457353
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Desmodium adscendens (FABACEAE) |
| Citation | MC MANUS,OB: HARRIS,GH: GIANGIACOMO,KM: FEIGENBAUM,P: REUBEN,JP: ADDY,ME: BURKA,JF: KACZOROWSKI,GJ: GARCIA,ML:. (1993). AN ACTIVATOR OF CALCIUM-DEPENDENT POTASSIUM CHANNELS ISOLATED FROM A MEDICINAL HERB.. 32(24) |
| Amount utilized | |
| Compound isolated | |
| Disease | CMPD ALLOSTERICALLY DESTABILLIZES BINDING OF LABELED CHARYBDOTOXIN. CMPD INCREASES OPEN PROBABILITY OF MAXI-K CHANNELS. CALCIUM WAS REQUIRED. |
| Dose amount | 5.0 MICROMOLS |
| Number | 6 |
| Qualitative result | ACTIVE |
| Animal | BULL |
| Dose expression | CONC USED |