Experiment 470572
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Empty organism |
| Citation | HERBERT,JM: SAVI,P: LAPLACE,MC: DUMAS,A: DOL,F:. (1993). CHELERYTHRINE, A SELECTIVE PROTEIN KINASE C INHIBITOR, COUNTERACTS PYROGEN-INDUCED EXPRESSION OF TISSUE FACTOR WITHOUT EFFECT ON THROMBOMODULIN DOWN-REGULATION IN ENDOTHELIAL CELLS.. 71(6) |
| Amount utilized | |
| Compound isolated | |
| Disease | VS.ENDOTOXIN, INDUCED UPREGULATION OF TISSUE FACTOR. CONCOMITANT DOWN REGULATION OF THROMBOMODULIN NOT ALTERED BY CMPD. |
| Dose amount | 45.0 MICROMOLS |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | BULL |
| Dose expression | IC50 |