Experiment 473223
Worktypes
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Haliclona viridis (HALICLONIDAE) |
| Citation | JAFFE,E: EISIG,M: SEVCIK,C:. (1993). EFFECT OF A TOXIN ISOLATED FROM THE SPONGE HALICLONA VIRIDIS ON THE RELEASE OF GAMMA-AMINOBUTYRIC ACID FROM RAT OLFACTORY BULB.. 31(4) |
| Amount utilized | |
| Compound isolated | |
| Disease | CONC. OF TOXIN EXPRESSED IN MILLI-MOUSE UNITS WHERE A MOUSE UNIT = LD-50 FOR MICE. COMPOND NOT ENTIRELY PURIFIED. EFFECT ASSAYED ON PRE-FRONTAL CORTEX. EFFECT DECREASED BY ABSENCE OF CA2+. TETRODOTOXIN OR REMOVAL OF NA+ HAD NO EFFECT. VALINOMYCIN INCREASED EFFECT. |
| Dose amount | 46.0 UNITS |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | RAT |
| Per unit | ML |
| Dose expression | CONC USED |
| Extract | TYPE EXT NOT STATED |