Experiment 477359

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CAMPTOTHECIN

Alerts

DATA INCOMPLETE - DERIVED FROM AN ABSTRACT.

Details

PropertyValue
Pharmacology
TOPOISOMERASE I INHIBITION
OrganismEmpty organism
CitationWOESSPER,RD: ENG,WK: HOFMANN,GA: RIEMAN,DJ: MC CABE,FL: HERTZBERG,RP: MATTERN,MR: TAN,KB: JOHNSON,RK:. (1992). CAMPTOTHECIN HYPER-RESISTANT P388 CELLS: DRUG-DEPENDENT REDUCTION IN TOPOLSOMERASE I CONTENT.. 4(11/12)
Amount utilized
Compound isolated
DiseaseCELLS MADE HIGHLY RESISTANT TO CAMPTOTHECIN SHOWED A DEFICINCY IN ENZYME ACTIVITY.
Number1
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionCONC USED