Experiment 477382

Worktypes

ANTICANCER AND/OR CYTOTOXICITY MARKER CODEPHARMACOLOGY OF EXTRACT - IN VIVO

Details

PropertyValue
Pharmacology
ANTITUMOR ACTIVITY
Administration routeIN RATION
OrganismCamellia sinensis (THEACEAE)
CitationHIROSE,M: HOSHIYA,T: AKAGI,K: TAKAHASHI,S: HARA,Y: ITO,N:. (1993). EFFECTS OF GREEN TEA CATECHINS IN A RAT MULTI-ORGAN CARCINOGENESIS MODEL.. 14(8)
Amount utilized
Compound isolated
DiseaseTHE NUMBERS OF SMALL INTESTINAL TUMORS(ADENOMAS AND CARCINOMAS) PER RAT WERE SIGNIFICANTLY REDUCED IN THE GROUPS TREATED WITH 0.1% GTC BOTH DURING AND AFTER CARCINOGEN EXPOSURE (0.46+0.97) AS COMPARED TO THE CARCINOGEN ALONE GROUP (1.07+1.21).
Dose amount.1 % OF DIET
Number2
Qualitative resultACTIVE
AnimalRAT(F344)
Dose expression-LOG(CONC.)
ExtractFLAVONOID FRACTION