Experiment 478577

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

HYDROQUINONE

Details

PropertyValue
Pharmacology
NEPHROTOXIC ACTIVITY
Administration routeINTRAGASTRIC
OrganismEmpty organism
CitationKARI,FW: BUCHER,J: EUSTIS,SL: HASEMAN,JK: HUFF,JE:. (1992). TOXICITY AND CARCINOGENICITY OF HYDROQUINONE IN F344/N RATS AND B6C3F-1 MICE.. 30(9)
Amount utilized
Compound isolated
DiseaseDOSED 5 TIMES WEEKLY FOR 2 YEARS. DEGENERATION OF TUBULAR EPITHELIUM, ATROPHY AND DILATATION OF TUBULES, GLOMERULOSIS, INTERSTITIAL FIBROSIS, CHRONIC INFLAMMATION AND ADENOMAS SEEN.
Dose amount50.0 MG
Number6
Qualitative resultACTIVE
AnimalRAT
Per unitKG
Dose expressionDOSE