Experiment 478965

Worktypes

CARCINOGENIC DATA (MARKER CODE)PHARMACOLOGY OF EXTRACT - IN VIVO

Alerts

VS.3'-METHYL-4-DIMETHYLAMINOAZOBENZENE-INDUCED CARCINOGENESIS.VS.12-O-TETRADECANOYLPHORBOL-13-ACETATE(TPA)-INDUCED CARCINOGENESIS.

Details

PropertyValue
Pharmacology
CARCINOGENESIS INHIBITION
Administration routeEXTERNAL
OrganismCamellia sinensis (THEACEAE)
CitationKATIYAR,SK: AGARWAL,R: MUKHTAR,H:. (1993). PROTECTION AGAINST MALIGNANT CONVERSION OF CHEMICALLY INDUCED BENIGN SKIN PAPILLOMAS TO SQUAMOUS CELL CARCINOMAS IN SENCAR MICE BY A POLYPHENOLIC FRACTION ISOLATED FROM GREEN TEA.. 53(22)
Amount utilized
Compound isolated
DiseaseMALIGNANT TUMOR CONVERSION ENHANCED BY TREATMENT WITH 4-NITROQUINOLINE-N-OXIDE WAS INHIBITED. PROTECTION MEASURED 43% IN MICE TREATED 2X WEEKLY.
Dose amount6.0 MG
Number3
Qualitative resultACTIVE
AnimalMOUSE
Per unitANIMAL
Dose expressionDOSE
ExtractPOLYPHENOLIC FRACTION