Experiment 480774
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IN RATION |
| Organism | Empty organism |
| Citation | TANAKA,T: KOJIMA,T: KAWAMORI,T: WANG,A: SUZUI,M: OKAMOTO,K: MORI,H:. (1993). INHIBITION OF 4-NITROQUINOLINE-1-OXIDE-INDUCED RAT TONGUE CARCINOGENESIS BY THE NATURALLY OCCURRING PLANT PHENOLICS CAFFEIC, ELLAGIC, CHLOROGENIC AND FERULIC ACIDS.. 14(7) |
| Amount utilized | |
| Compound isolated | |
| Disease | IN THE PRESENT STUDY, RATS WERE FED A DIET CONTAINING 250 PPM CHLOROGENIC ACID FOR 7 WKS DURING THE INITIATION PHASE OF 4-NITROQUINOLINE-1-OXIDE INDUCED TONGUE CARCINOGENESIS. DIETARY ADMINISTRATION OF CGA CLEARLY SUPPRESSED TUMOR DEVELOPMENT AND INHIBITED THE OCCURRENCE OF PRENEOPLASTIC LESIONS OF THE TONGUS SQUAMOUS EPITHELIUM. |
| Dose amount | 250.0 PPM |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | RAT(F344) |
| Dose expression | DOSE |