Experiment 481183

Worktypes

ANTICANCER AND/OR CYTOTOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

INTEGERRIMINE

Alerts

ASSAY SYSTEM IS INTENDED TO PREDICT FOR ANTITUMOR ACTIVITY.DATA INCOMPLETE - DERIVED FROM AN ABSTRACT.

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismEmpty organism
CitationPAULA-RAMOS,ALL: QUEROL,CB: MARQUES,EK: HENRIQUES,JAP:. (1991). CYTOTOXIC ACTIVATION OF THE PYRROLIZIDINE ALKALOID INTEGERRIMINE IN THE YEAST SACCHARIOMYCES CEREVISIAE IS CAUSED BY REPAIRABLE DNA DAMAGE.. 14(4)
Amount utilized
Compound isolated
DiseaseTHE CYTOSTATIC AND CYTOTOXIC EFFECTS OF ITR DEPEND ON THE DNA REPAIR CAPACITY AND ON ALKALOID CONCENTRATION.
Number1
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionCONC USED