Experiment 483180

Worktypes

EFFECTS DUE TO A COMBINATION OF DRUGSANTICANCER AND/OR CYTOTOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

TAXOL

Alerts

A MIXTURE OF PURE COMPOUNDS WAS USED TO OBTAIN THE REPORTED EFFECT.

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismEmpty organism
CitationHAHN,SM: LIEBMANN,JE: COOK,J: FISHER,J: GOLDSPIEL,B: VENZON,D: MITCHELL,JB: KAUFMAN,D:. (1993). TAXOL IN COMBINATION WITH DOXORUBICIN OR ETOPOSIDE.. 72(9)
Amount utilized
Compound isolated
DiseaseNO SYNERGISTIC CYTOTOXICITY WAS OBSERVED WITH A COMBINED TREATMENT OF TAXOL AND DOXORUBICIN, 4.0 MCG/C. THE SURVIVAL CURVES SHOWED LESS THAN ADDITIVE EFFECT.
Dose amount100.0 NANOMOLS
Number1
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionCONC USED