Experiment 483227
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Empty organism |
| Citation | LIEBMANN,JE: HAHN,SM: COOK,JA: LIPSCHULTZ,C: MITCHELL,JB: KAUFMAN,DC:. (1993). GLUTATHIONE DEPLETION BY L-BUTHIONINE SULFOXIMINE ANTAGONIZES TAXOL CYTOTOXICITY.. 53(9) |
| Amount utilized | |
| Compound isolated | |
| Disease | CELLS WERE TREATED WITH L-BUTHIONINE SULFOXIMINE WHICH REDUCED GLUTHATHIONE LEVELS. CELLS SHOWED A 10-FOLD INCREASE IN SURVIVAL OVER NON-GLUTHATHIONE DEPLETED CELLS. |
| Dose amount | 50.0 NANOMOLS |
| Number | 4 |
| Qualitative result | ACTIVE |
| Animal | CELL CULTURE |
| Dose expression | CONC USED |