Experiment 486914

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODEPATENT DESCRIBED

Compounds isolated

CAMPTOTHECIN,10-11-METHYLENEDIOXY: 20(RS):

Alerts

BIOLOGICAL ACTIVITY REPORTED HAS BEEN PATENTED.DATA INCOMPLETE - DERIVED FROM AN ABSTRACT.

Details

PropertyValue
Pharmacology
ANTITUMOR ACTIVITY
Administration routeIP
OrganismEmpty organism
CitationGIOVANNELLA,BC: LIU,LF: POTMESIL,M: WALL,MC: SILBER,RF: WANI,MC:. (1993). TREATMENT OF COLON TUMORS WITH CAMPTOTHECIN COMPOUNDS.. ()
Amount utilized
Compound isolated
DiseaseINHIBITS COLON AND COLORECTAL TUMORS. MECHANISM OF ACTION INVOLVES INHIBITION OF DNA TOPOISOMERASE I ACTIVITY.
Dose amount70.0 MG
Number1
Qualitative resultACTIVE
AnimalMOUSE
Per unitKG
Dose expressionDOSE