Experiment 489364
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IV INFUSION |
| Organism | Empty organism |
| Citation | PAZDUR,R: KUDELKA,AP: KAVANAGH,JJ: COHEN,PR: RABER,MN:. (1993). THE TAXOIDS: PACILTAXEL (TAXOL) AND DOCETAXEL (TAXOTERE).. 19(4) |
| Amount utilized | |
| Compound isolated | |
| Disease | USING A 3-HOUR INFUSION OF PACLITAXEL EVERY 21 DAYS, INVESTIGATORS NOTED THREE OF FIVE PATIENTS TREATED DEVELOPED HYPERSENSITIVITY REACTIONS. CHARACTERIZED BY ACUTE DYSPNEA, GENERALIZED ERYTHEMA, OR HYPOTENSION. THIS IS PHASE I TRIAL. |
| Dose amount | 190.0 MG |
| Number | 4 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Per unit | SQ M |
| Dose expression | DOSE |