Experiment 489466

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

THIOCYANATE,ISO: PHENETHYL:

Details

PropertyValue
Pharmacology
METABOLISM INHIBITION
OrganismEmpty organism
CitationMURPHY,SE: HEIBLUM,R: KING,PG: BOWMAN,D: DAVIS,WJ: STONER,GD:. (1991). EFFECT OF PHENETHYL ISOTHIOCYANATE ON THE METABOLISM OF TOBACCO-SPECIFIC NITROSAMINES BY CULTURED RAT ORAL TISSUE.. 12(6)
Amount utilized
Compound isolated
DiseaseALPHA-HYDROXYLATION AND N-OXIDATION OF 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE INHIBITED. CARBONYL REDUCTION INHIBITED ONLY SLIGHTLY.
Dose amount10.0 MICROMOLS
Number2
Qualitative resultACTIVE
AnimalRAT
Dose expressionCONC USED