Experiment 494368

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

TAXOL

Alerts

DATA INCOMPLETE - DERIVED FROM AN ABSTRACT.

Details

PropertyValue
Pharmacology
DRUG RESISTANCE REVERSAL INDUCTION
OrganismEmpty organism
CitationSYED,SK: CHRISTOPHERSON,RI: ROUFOGALIS,BD:. (1993). VINBLASTINE TRANSPORT BY MEMBRANE VESICLES FROM HUMAN MULTIDRUG-RESISTANT CCRF-CEM LEUKEMIA CELLS: INHIBITION BY TAXOL AND MEMBRANE PERMEABILIZING AGENTS.. 30(4)
Amount utilized
Compound isolated
DiseaseCMPD INHIBITED ATP-DEPENDENT ACTIVE TRANSPORT OF VINBLASTIN FROM RESISTANT CELLS AND PROMOTED DIFFUCION ACROSS CELL MEMBRANE.
Dose amount1.0 MICROMOLS
Number1
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50