Experiment 506969
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | PERFUSION |
| Organism | Empty organism |
| Citation | YAN,CC: HUXTABLE,RJ:. (1994). QUANTITATION OF THE HEPATIC RELEASE OF METABOLITES OF THE PYRROLIZIDINE ALKALOID, MONOCROTALINE.. 127(1) |
| Amount utilized | |
| Compound isolated | |
| Disease | PYRROLIZIDINE ALKALOIDS SUCH AS MONOCROTALINE ARE BIOACTIVATED IN THE LIVER TO PNEUMOTOXINS THAT CAUSE PULMONARY ARTERIAL HYPERTENSION AND RIGHT VENTRICULAR HYPERTROPHY. |
| Dose amount | 5.0 NANOMOLS |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | RAT |
| Per unit | HOUR |
| Dose expression | DOSE |
| Gender | MALE |