Experiment 511658

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

BRYOSTATIN 1

Details

PropertyValue
Pharmacology
PROTEIN KINASE C INHIBITION
OrganismEmpty organism
CitationSZALLASI,Z: DENNING,MF: SMITH,CB: DLUGOSZ,AA: YUSPA,SH: PETTIT,GR: BLUMBERG,PM:. (1994). BRYOSTATIN 1 PROTECTS PROTEIN KINASE C-O FROM DOWN-REGULATION IN MOUSE KERATINOCYTES IN PARALLEL WITH ITS INHIBITION OF PHORBOL ESTER-INDUCED DIFFERENTIATION.. 46(5)
Amount utilized
Compound isolated
DiseaseDOWN REGULATION OF PKC-ALPHA.
Dose amount0.3 NANOMOLS
Number2
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionED50