Experiment 514505

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CAMPTOTHECIN

Details

PropertyValue
Pharmacology
TOPOISOMERASE I INHIBITION
OrganismEmpty organism
CitationLUZZIO,MJ: BESTERMAN,JM: EMERSON,DL: EVANS,MG: LACKEY,K: LEITNER,PL: MC INTYRE,G: MORTON,B: MYERS,PL: PEEL,M: SISCO,JM: STERNBACH,DD: TONG,WQ: TRUESDA:. (1995). SYNTHESIS AND ANTITUMOR ACTIVITY OF NOVEL WATER SOLUBLE DERIVATIVES OF CAMPTOTHECIN AS SPECIFIC INHIBITORS OF TOPOISOMERASE I.. 38(3)
Amount utilized
Compound isolated
Dose amount670.0 NANOMOLS
Number2
Qualitative resultACTIVE
Dose expressionIC50