Experiment 514509

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CAMPTOTHECIN

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismEmpty organism
CitationLUZZIO,MJ: BESTERMAN,JM: EMERSON,DL: EVANS,MG: LACKEY,K: LEITNER,PL: MC INTYRE,G: MORTON,B: MYERS,PL: PEEL,M: SISCO,JM: STERNBACH,DD: TONG,WQ: TRUESDA:. (1995). SYNTHESIS AND ANTITUMOR ACTIVITY OF NOVEL WATER SOLUBLE DERIVATIVES OF CAMPTOTHECIN AS SPECIFIC INHIBITORS OF TOPOISOMERASE I.. 38(3)
Amount utilized
Compound isolated
Dose amount48.0 NANOMOLS
Number6
Qualitative resultSTRONG ACTIVITY
AnimalCELL CULTURE
Dose expressionIC50