Experiment 514535

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

OCTADECA-9-CIS-14-DIENOIC ACID,12-13-16-TRIHYDROXY:OCTADECA-CIS-9-TRANS-13-DIENOIC ACID,12-15-16-TRIHYDROXY:OCTADECA-CIS-9-TRANS-14-DIENOIC ACID,12-13-16-TRIHYDROXY:OCTADECA-TRANS-11-CIS-15-DIENOIC ACID,9-10-13-TRIHYDROXY:

Details

PropertyValue
Pharmacology
ANTIATHEROSCLEROTIC ACTIVITY
OrganismBryonia alba (CUCURBITACEAE)
CitationOREKHOV,AN: PANOSSIAN,AG:. (1994). TRIHYDROXYOCTADECADIENOIC ACIDS EXHIBIT ANTIATHEROSCLEROTIC AND ANTIATHEROGENIC ACTIVITY.. 1(2)
Amount utilized
Compound isolated
DiseaseREDUCED CHOLESTEROL CONTENT IN SUBENDOTHELIAL CELL CULTURES, AS WELL AS THYMIDINE INCORPORATION.
Dose amount0.56 MICROMOLS
Number2
Qualitative resultACTIVE
AnimalHUMAN ADULT
Dose expressionED50