Experiment 516968

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

RESIBUFOGENIN-3-SULFATE,12-BETA-HYDROXY-TETRAHYDRO:

Details

PropertyValue
Pharmacology
ATP-ASE(NA+/K+) INHIBITION
OrganismBufo marinus (BUFONIDAE)
CitationLEE,SS: DERGUINI,F: BRUENING,RC: NAKANISHI,K: WALLICK,ET: AKIZAWA,T: ROSENBAUM,CS: BULTER JR,VP:. (1994). DIGITALIS-LIKE COMPOUNDS OF TOAD BILE: SULFATION AND REDUCTION OF BUFADIENOLIDES DECREASE POTENCY OF NA+,K+-ATPASE INHIBITION.. 39(2)
Amount utilized
Compound isolated
Dose amount300.0 MICROMOLS
Number2
Qualitative resultWEAK ACTIVITY
Dose expressionIC50