Experiment 516970

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

MARINOBUFAGIN-3-SULFATE

Details

PropertyValue
Pharmacology
ATP-ASE(NA+/K+) INHIBITION
OrganismBufo marinus (BUFONIDAE)
CitationLEE,SS: DERGUINI,F: BRUENING,RC: NAKANISHI,K: WALLICK,ET: AKIZAWA,T: ROSENBAUM,CS: BULTER JR,VP:. (1994). DIGITALIS-LIKE COMPOUNDS OF TOAD BILE: SULFATION AND REDUCTION OF BUFADIENOLIDES DECREASE POTENCY OF NA+,K+-ATPASE INHIBITION.. 39(2)
Amount utilized
Compound isolated
Dose amount2.79 MICROMOLS
Number4
Qualitative resultSTRONG ACTIVITY
Dose expressionIC50