Experiment 517307

Worktypes

ANTICANCER AND/OR CYTOTOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

SAPORIN

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismSaponaria officinalis (CARYOPHYLLACEAE)
CitationBONARDI,MA: FRENCH,RR: AMLOT,P: GROMO,G: MODENA,D: GLENNIA,MJ:. (1993). DELIVERY OF SAPORIN TO HUMAN B-CELL LYMPHOMA USING BISPECIFIC ANTIBIODY: TARGETING VIA CD22 BUT NOT CD19, CD37, OR IMMUNOGLOBULIN RESULTS IN EFFICIENT KILLING.. 53(13)
Amount utilized
Compound isolated
DiseaseBISPECIFIC ANTIBODIES USED TO TARGET CMPD TO CD22 PROTEIN ON CELL SURFACE.
Dose amount0.3 NANOMOLS
Number2
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionED50