Experiment 518671

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

PENITREM A

Details

PropertyValue
Pharmacology
POTASSIUM CHANNEL BLOCKING ACTIVITY
OrganismEmpty organism
CitationKNAUS,HG: MC MANUS,OB: LEE,SH: SCHMALHOFER,WA: GARCIA-CALVO,M: HELMS,LMH: SANCHEZ,M: GIANGIACOMO,K: REUBEN,JP: SMITH III,AB: KACZOROWSKI,GJ: GARCIA,ML:. (1994). TREMORGENIC INDOLE ALKALOIDS POTENTLY INHIBIT SMOOTH MUSCLE HIGH-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS.. 33(19)
Amount utilized
Compound isolated
DiseaseCOMPOUND ALLOSTERICALLY INHIBITED BINDING OF LABELED CHARYBDOTOXIN TO MAXI-K CHANNELS.
Dose amount1.7 MICROMOLS
Number4
Qualitative resultACTIVE
AnimalBULL
Dose expressionCONC USED