Experiment 521343

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

RADICICOL

Details

PropertyValue
Pharmacology
CYCLOOXYGENASE INHIBITION
Administration routeINTRAARTERIAL
OrganismEmpty organism
CitationCHANMUGAM,P: FENG,L: LIOU,S: LANG,BC: BOUDREAU,M: YU,G: LEE,JH: KWON,HJ: BEPPU,T: YOSHIDA,M: XIA,YY: WILSON,CB: HWANG,D:. (1995). RADICICOL, A PROTEIN TYROSINE KINASE INHIBITOR, SUPPRESSES THE EXPRESSION OF MITOGEN-INDUCIBLE CYCLOOXYGENASE IN MACROPHAGES STIMULATED WITH LIPOPOLYSACCHARIDE AND IN EXPERIMENTAL GLOMERULONEPHRITIS.. 270(10)
Amount utilized
Compound isolated
DiseaseVS.CYCLOOXYGENASE-2 EXPRESSION SEEN IN ANTI-GLOMERULAR BASEMENT MEMBRANE ANTIBODY-INDUCED GLOMERULONEPHRITIS.
Dose amount100.0 MCG
Number3
Qualitative resultACTIVE
AnimalRAT
Per unitKG
Dose expressionDOSE