Experiment 521507
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IN RATION |
| Organism | Empty organism |
| Citation | YUAN,JH: GOEHL,TJ: ABDO,K: CLARK,J: ESPINOSA,O: BUGGE,C: GARCIA,D:. (1995). EFFECTS OF GAVAGE VERSUS DOSED FEED ADMINISTRATION ON THE TOXICOKINETICS OF BENZYL ACETATE IN RATS AND MICE.. 33(2) |
| Amount utilized | |
| Compound isolated | |
| Disease | STUDY OF EFFECT OF IG VS. IN DIET DOSING OF CMPD. GAVAGE DOSING APPEARS TO SATURATE METABOLIC PATHWAY ALTHOUGH HIPPURIC ACID CONC. (FINAL METABOLITE) WERE SIMILAR IN BOTH CASES. THIS MIGHT EXPLAIN DIFFERENTIAL TOXICITY: GAVAGE LEADS TO HEPATIC TUMORIGENICITY AND PANCREATIC ADENOMAS NOT SEEN IN DOSED FEED. |
| Dose amount | 850.0 MG |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | MOUSE |
| Per unit | KG |
| Dose expression | DOSE |